In intensive care units, up to 30% of A. baumannii clinical isolates are resistant to at least three classes of antibiotics, often including fluoroquinolones and carbapenems.
The circadian clock of cyanobacteria is different from all other known clocks, consisting of just three proteins which time phosphorylation and dephosphorylation on 24-hour rhythms even in vitro.
Nothing stimulates immunity as well as the infection itself; hence, in a vaccine, use of an organism with a mutation that eliminates pathogenicity is optimal.